Mutants suppressing in trans chorion gene amplification in Drosophila.
- 1 June 1984
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 81 (12) , 3773-3777
- https://doi.org/10.1073/pnas.81.12.3773
Abstract
Two recessive female-sterile mutants, K451 and K1214, disrupt chorion formation by causing underproduction of all major chorion proteins. Evidently, this effect is due to underaccumulation of the chorion mRNA and this is caused by a substantial reduction in the level of chorion gene amplification. The mutants are X-linked but located at 2 sites far from the chorion gene cluster at 7F1-2; their effect is even more pronounced on the 3rd chromosome chorion gene cluster, and, thus, the wild type gene must act in trans. The time course of amplification in mutant and wild-type follicles is documented.Keywords
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