TICO: a tool for improving predictions of prokaryotic translation initiation sites
Open Access
- 30 June 2005
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 21 (17) , 3568-3569
- https://doi.org/10.1093/bioinformatics/bti563
Abstract
Summary: We provide the tool ‘TICO’ (Translation Initiation site COrrection) for improving the results of conventional gene finders for prokaryotic genomes with regard to exact localization of the translation initiation site (TIS). At the current state TICO provides an interface for direct post processing of the predictions obtained from the widely used program GLIMMER. Our program is based on a clustering algorithm for completely unsupervised scoring of potential TIS locations. Availability: Our tool can be freely accessed through a web interface at http://tico.gobics.de/ Contact:maike@gobics.deKeywords
This publication has 8 references indexed in Scilit:
- Oligo kernels for datamining on biological sequences: a case study on prokaryotic translation initiation sitesBMC Bioinformatics, 2004
- Accuracy improvement for identifying translation initiation sites in microbial genomesBioinformatics, 2004
- GS-Finder: a program to find bacterial gene start sites with a self-training methodThe International Journal of Biochemistry & Cell Biology, 2003
- A probabilistic method for identifying start codons in bacterial genomesBioinformatics, 2001
- GeneMarkS: a self-training method for prediction of gene starts in microbial genomes. Implications for finding sequence motifs in regulatory regionsNucleic Acids Research, 2001
- Artemis: sequence visualization and annotationBioinformatics, 2000
- EcoGene: a genome sequence database for Escherichia coli K-12Nucleic Acids Research, 2000
- Improved microbial gene identification with GLIMMERNucleic Acids Research, 1999