Evidence for a "Pro-relaxin" in Porcine Relaxin Concentrates

Abstract
From 5-10% of the biological activity of a porcine relaxin concentrate is contained in a fraction with a MW which is considerably higher (.apprx. 42,000 daltons) than that of relaxin itself. Exposure of this material to a low concentration of trypsin results in the appearance of native relaxin, as judged by an increase in biological activity and changes in its chromatographic and electrophoretic properties.

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