Subunit exchange and ligand binding: a new hypothesis for the mechanism of oxygenation of hemoglobin.
- 1 August 1965
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 54 (2) , 535-542
- https://doi.org/10.1073/pnas.54.2.535
Abstract
Oxygenation of hemoglobin Involves a reaction in which oxygenated a{l dlmers exchange with deoxygenated ([alpha][beta])2 tetramers to form mixed molecules with a high O2 affinity. Oxy dimers act as allosteric effectors which bring about flie transformation of the molecule from an unreactive to a reactive conformation.This publication has 22 references indexed in Scilit:
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