Radiological study of pleural changes in relation to mesothelioma in Turkey.

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Abstract
In some villages in central Turkey pleural changes occur as a result of environmental exposure to mineral fibers. In most cases the fiber is asbestos but in some cases the non-asbestos fiber erionite, a zeolite, is responsible. The incidence of malignant mesothelioma is much higher in erionite villages than in asbestos villages despite similar frequencies of pleural changes. Chest radiographs from 466 people from asbestos villages, 549 from erionite villages, and 382 controls were compared. The frequency of pleural calcification was about the same in the 2 groups of villages studied, but the minor fissures were visible to a greater degree in erionite cases. In people from erionite villages atypical pleural calcification, due to calcification of the visceral rather than the parietal pleura, was more common. These differences may indicate that the fibers have different lengths and diameters.