The reaction of glutathione with the eye-lens protein γ-crystallin
Open Access
- 15 August 1985
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 230 (1) , 143-150
- https://doi.org/10.1042/bj2300143
Abstract
Lens cells contain high concentrations of thiol-rich proteins, γ-crystallins and reduced glutathione. Solutions of bovine γ-crystallin react avidly with either reduced or oxidized glutathione to form protein-glutathione mixed disulphides. A method of purification of a γ-II crystallin-glutathione adduct containing two mixed disulphide groups is described.This publication has 26 references indexed in Scilit:
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