Direct Percutaneous Transluminal Angioplasty for Acute Middle Cerebral Artery Trunk Occlusion
- 1 December 2002
- journal article
- clinical trial
- Published by Wolters Kluwer Health in Stroke
- Vol. 33 (12) , 2872-2876
- https://doi.org/10.1161/01.str.0000038985.26269.f2
Abstract
Background and Purpose— The purpose of this study was to evaluate the safety and efficacy of direct percutaneous transluminal angioplasty (PTA) for patients with acute middle cerebral artery (MCA) trunk occlusion. Methods— Over the past 9 years, a total of 70 patients with acute MCA trunk occlusion were treated with intra-arterial reperfusion therapy. In the last 5 years, 34 patients were treated with direct PTA, and subsequent thrombolytic therapy was added if necessary for distal embolization. The other 36 patients, mainly in the first 4 years, were treated with thrombolytic therapy alone and were used as controls. Pretherapeutic neurological status was evaluated with National Institutes of Health Stroke Scale scores. The modified Rankin Scale (mRS) was used to assess clinical outcome at 90 days. Results— There were no significant differences in pretherapeutic National Institutes of Health Stroke Scale score and duration of ischemia between the 2 groups. The rate of partial or complete recanalization in...Keywords
This publication has 12 references indexed in Scilit:
- Intra-arterial Prourokinase for Acute Ischemic StrokeJAMA, 1999
- Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)Published by Elsevier ,1998
- Direct percutaneous transluminal angioplasty for acute embolic middle cerebral artery occlusion: Report of two casesInternational Journal of Angiology, 1997
- Prediction of Hemorrhagic Complications after Thrombolytic Therapy for Middle Cerebral Artery Occlusion: Value of Pre- and Post-therapeutic Computed Tomographic Findings and Angiographic Occlusive SiteNeurosurgery, 1996
- Thrombolytic Therapy with Streptokinase in Acute Ischemic StrokeNew England Journal of Medicine, 1996
- Tissue Plasminogen Activator for Acute Ischemic StrokeNew England Journal of Medicine, 1995
- Randomised controlled trial of streptokinase, aspirin, and combination of both in treatment of acute ischaemic strokeThe Lancet, 1995
- Intravenous Thrombolysis With Recombinant Tissue Plasminogen Activator for Acute Hemispheric StrokeJAMA, 1995
- Transluminal angioplasty for atherosclerotic disease of the vertebral and basilar arteriesJournal of Neurosurgery, 1993
- The Thrombolysis in Myocardial Infarction (TIMI) TrialNew England Journal of Medicine, 1985