Microbial Production of Tenuazonic Acid Analogues
Open Access
- 1 February 1973
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 3 (2) , 308-309
- https://doi.org/10.1128/aac.3.2.308
Abstract
The fungus Alternaria tenuis normally produces tenuazonic acid (3-acetyl-5-secbutyltetramic acid). On supplementation of the culture substrate with l -valine and l -leucine, the organism formed two new tetramic acids, 3-acetyl-5-isopropyltetramic acid and 3-acetyl-5-isobutyltetramic acid, respectively. l -Phenylalanine was not utilized by the organism as a tetramic acid precursor.Keywords
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