Heilmittelchemische Untersuchungen in der heterocyclischen Reihe. Mitteilung. Pyrazolo‐(3,4‐d)‐pyrimidine
- 1 January 1956
- journal article
- research article
- Published by Wiley in Helvetica Chimica Acta
- Vol. 39 (3) , 986-991
- https://doi.org/10.1002/hlca.19560390345
Abstract
The synthesis of 4‐ and 6‐substituted 1‐H‐ and 1‐phenyl‐pyrazolo‐(3,4‐d)‐pyrimidines is described. It starts from ethyl ethoxymethylene cyanoacetate from which the 4‐hydroxy‐pyrazolo‐(3,4‐d)‐ pyrimidines can be obtained in two steps through the corresponding 2‐substituted 3‐amino‐4‐carbethoxy‐pyrazoles.Keywords
This publication has 3 references indexed in Scilit:
- Potential Purine Antagonists. I. Synthesis of Some 4,6-Substituted Pyrazolo [3,4-d] pyrimidines1Journal of the American Chemical Society, 1956
- Inhibition of Experimental Neoplasms by 4-Aminopyrazolo(3,4-d)Pyrimidine.Experimental Biology and Medicine, 1955
- Studies in Chemotherapy. VIII. Methionine and Purine Antagonists and their Relation to the Sulfonamides1Journal of the American Chemical Society, 1945