PROGNOSIS AFTER TREATMENT OF VILLOUS ADENOMAS OF THE COLON AND RECTUM

  • 1 January 1979
    • journal article
    • research article
    • Vol. 189  (4) , 404-408
Abstract
With the existing evidence of neoplastic polyps of the colon and rectum as precursors of most or all colonic cancer, information of the short- and long-term course after treatment is a prerequisite of using the knowledge of the polyp-cancer sequence in an effective cancer prophylaxis. Patients (174) treated for villous adenomas of the colon and rectum during 1960-1975 were re-examined. Survival and cure rates were estimated by actuarial analysis. The death rate of colonic cancer among patients treated for a benign villous adenoma was significantly higher than in an age- and sex-matched normal population, resulting in a significantly reduced crude survival rate among these patients. Almost all recurrences after treatment of benign villous adenomas occurred within the first 4-5 yr resulting in a cumulative 5 yr recurrence rate of roughly 30%, indicating that 5 yr seem to be an adequate total control period following treatment.

This publication has 14 references indexed in Scilit: