Reactive Perforating Collagenosis

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Abstract
Reactive perforating collagenosis is a recently-recognized entity, in which a series of epidermal changes lead to elimination of altered collagen bundles through the transepidermal route. Clinically the disease is manifested by the appearance of asymptomatic papules which develop a central umbilication and then disappear spontaneously in 6–8 weeks. A necrobiotic change of collagen in response to trauma in genetically-predisposed individuals is considered to be of etiologic significance. The authors describe a typical case in which a distinct improvement in summer months was regularly recorded for the last 20 years.

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