Enamel Fluoride Uptake and Retention from Intensive APF Gel Applications In Vivo

Abstract
Children in a fluor dated water area self-applied acidulated phosphate fluoride (APF) gel (pH3.2) on 5, 10, or 25 consecutive school days. Analysis of exfoliated deciduous teeth showed that F concentrations in enamel increased to high levels during the treatment periods. Following the treatments, F levels decreased significantly for 2-10 months, after which the remaining F appeared permanently bound.