Structure of the α1 subunit of horse Na,K‐ATPase gene
- 19 June 1989
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 250 (1) , 91-98
- https://doi.org/10.1016/0014-5793(89)80691-x
Abstract
Genomic DNA for Na,K-ATPase α1 subunit was obtained from libraries of horse kidney genomic DNA in Charon 4A and in EMBL3 bacteriophages by screening with the full sized cDNA probe of the α1 subunit of rat Na,K-ATPase as probe. The gene spans 30 kb and consists of 23 exons and 22 intervening sequences. Intron-exon boundaries were analyzed. The protein-coding nucleotide sequence encodes 1016 amino acids with an M r of 112 264. The putative amino acid sequence of horse α1 is 96–97% homologous to those of other mammalian species.Keywords
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