Epitopes on Rh Proteins
- 1 July 2000
- journal article
- Published by Wiley in Vox Sanguinis
- Vol. 78 (S2) , 117-120
- https://doi.org/10.1111/j.1423-0410.2000.tb00048.x
Abstract
Analyses of the reactions of monoclonal anti‐D with Rh D variant red cells have shown that there are at least 24 different epitopes of the Rh D antigen. Similar studies Of Rh E variant red cells with monoclonal anti‐E indicate that there are at least 4 epitopes of the Rh E antigen. The relation of these serologically defined epitopes to the structure of the Rh proteins is reviewed. Most epitopes are discontinuous, with critical residues present in different loops of the proteins.This publication has 21 references indexed in Scilit:
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