PharmGKB: the Pharmacogenetics Knowledge Base
Top Cited Papers
Open Access
- 1 January 2002
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 30 (1) , 163-165
- https://doi.org/10.1093/nar/30.1.163
Abstract
The Pharmacogenetics Knowledge Base (PharmGKB; http://www.pharmgkb.org/) contains genomic, phenotype and clinical information collected from ongoing pharmacogenetic studies. Tools to browse, query, download, submit, edit and process the information are available to registered research network members. A subset of the tools is publicly available. PharmGKB currently contains over 150 genes under study, 14 Coriell populations and a large ontology of pharmacogenetics concepts. The pharmacogenetic concepts and the experimental data are interconnected by a set of relations to form a knowledge base of information for pharmacogenetic researchers. The information in PharmGKB, and its associated tools for processing that information, are tailored for leading-edge pharmacogenetics research. The PharmGKB project was initiated in April 2000 and the first version of the knowledge base went online in February 2001.Keywords
This publication has 6 references indexed in Scilit:
- AUTOMATING DATA ACQUISITION INTO ONTOLOGIES FROM PHARMACOGENETICS RELATIONAL DATA SOURCES USING DECLARATIVE OBJECT DEFINITIONS AND XMLPacific Symposium on Biocomputing, 2001
- Integrating genotype and phenotype information: an overview of the PharmGKB projectThe Pharmacogenomics Journal, 2001
- dbSNP: the NCBI database of genetic variationNucleic Acids Research, 2001
- VISTA : visualizing global DNA sequence alignments of arbitrary lengthBioinformatics, 2000
- Pharmacogenomics: Translating Functional Genomics into Rational TherapeuticsScience, 1999
- HinCyc: a knowledge base of the complete genome and metabolic pathways of H. influenzae.1996