Penicillin acylase-catalyzed synthesis of β-lactam antibiotics in water-methanol mixtures: effect of cosolvent content and chemical nature of substrate on reaction rates and yields
- 30 June 1996
- journal article
- Published by Elsevier in Journal of Molecular Catalysis B: Enzymatic
- Vol. 1 (3-6) , 201-211
- https://doi.org/10.1016/1381-1177(96)00007-0
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- Penicillin acylase-catalyzed synthesis of pivampicillin: Effect of reaction variables and organic cosolventsJournal of Molecular Catalysis B: Enzymatic, 1996
- Effect of water activity on thermolysin-catalyzed peptide synthesis in organic solventsBiotechnology Letters, 1995
- Enzyme reaction engineering: Synthesis of antibiotics catalysed by stabilized penicillin G acylase in the presence of organic cosolventsEnzyme and Microbial Technology, 1991
- Equilibrium controlled synthesis of cephalothin in water-cosolvent systems by stabilized penicillin G acylaseApplied Biochemistry and Biotechnology, 1991
- [26] Equilibrium and kinetically controlled synthesis with enzymes: Semisynthesis of penicillins and peptidesPublished by Elsevier ,1987
- Mechanism and yields in enzyme catalysed equilibrium and kinetically controlled synthesis of β-lactam antibiotics, peptides and other condensation productsEnzyme and Microbial Technology, 1986
- Basic Principles of Protease‐Catalyzed Peptide Bond FormationAngewandte Chemie International Edition in English, 1985
- Peptide synthesis in aqueous–organic solvent mixtures with α‐chymotrypsin immobilized to tresyl chloride‐activated agaroseBiotechnology & Bioengineering, 1984
- Synthesis of peptide bonds by proteinases. Addition of organic cosolvents shifts peptide bond equilibriums toward synthesisBiochemistry, 1978
- Reversal of enzymatic hydrolysis: Rate and extent of ester synthesis as catalyzed by chymotrypsin and subtilisin Carlsberg at low water concentrationsBiotechnology & Bioengineering, 1975