Biogerontology: The Next Step
- 1 June 2000
- journal article
- review article
- Published by Wiley in Annals of the New York Academy of Sciences
- Vol. 908 (1) , 282-290
- https://doi.org/10.1111/j.1749-6632.2000.tb06655.x
Abstract
After a long period of collecting empirical data describing the changes in organisms, organs, tissues, cells, and macromolecules, biogerontological research is now able to develop various possibilities for intervention. Because aging is a stochastic and nondeterministic process characterized by a progressive failure of maintenance and repair, it is reasoned that genes involved in homeodynamic repair pathways are the most likely candidate gerontogenes. A promising approach for the identification of critical gerontogenic processes is through the hormesis‐like positive effects of mild stress. Stimulation of various repair pathways by mild stress has significant effects on delaying the onset of various age‐associated alterations in cells, tissues, and organisms.Keywords
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