Adrenal Cortical Neoplasms in the Pediatric Population
Top Cited Papers
- 1 July 2003
- journal article
- research article
- Published by Wolters Kluwer Health in The American Journal of Surgical Pathology
- Vol. 27 (7) , 867-881
- https://doi.org/10.1097/00000478-200307000-00001
Abstract
Adrenal cortical neoplasms in pediatric patients (400 g), tumor size (>10.5 cm), vena cava invasion, capsular and/or vascular invasion, extension into periadrenal soft tissue, confluent necrosis, severe nuclear atypia, >15 mitotic figures/20 high power fields, and the presence of atypical mitotic figures. Vena cava invasion, necrosis, and increased mitotic activity (>15 mitotic figures/20 high power fields) independently suggest malignant clinical behavior in multivariate analysis.Keywords
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