Urinary Kallikrein Excretion in Normotensive and Spontaneously Hypertensive Rats

Publisher Website
Google Scholar
Abstract
Using single animals and repeated determinations at one week intervals the urine output, and sodium and kallikrein urinary excretion have been measured in normotensive, “moderate” spontaneously hypertensive (BP 150–179 mmHg) and “elevated” spontaneously hypertensive rats (BP > 180 mmHg). Both the groups of spontaneously hypertensive rats show higher water, sodium and kallikrein excretions than the normotensive animals. The group of “elevated” hypertensive rats shows the highest values. The results are discussed in the light of the interrelation between the kallikrein‐kinin system and the prostaglandis.