Irinotecan and 5-Fluorouracil in colorectal cancer: time for a pause?
- 1 February 1998
- journal article
- Published by Elsevier in European Journal Of Cancer
- Vol. 34 (3) , 286-289
- https://doi.org/10.1016/s0959-8049(97)10064-8
Abstract
No abstract availableKeywords
This publication has 22 references indexed in Scilit:
- Sister chromatid exchange induced by DNA topoisomerases poisons in late replicating heterochromatin: influence of inhibition of replication and transcriptionMutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1996
- CPT-11 (Irinotecan) in the treatment of colorectal cancerEuropean Journal Of Cancer, 1995
- Cellular Determinants of Sensitivity and Resistance to DNA Topoisomerase InhibitorsCancer Investigation, 1994
- Phase II study of CPT-11, a new camptothecin derivative, in metastatic colorectal cancer. CPT-11 Gastrointestinal Cancer Study Group.Journal of Clinical Oncology, 1993
- Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project.Journal of Clinical Oncology, 1992
- Effects of CPT‐11 in combination with other anti‐cancer agents in cultureInternational Journal of Cancer, 1992
- Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNANucleic Acids Research, 1991
- DNA Topoisomerase I—Targeted Chemotherapy of Human Colon Cancer in XenograftsScience, 1989
- DNA TOPOISOMERASE POISONS AS ANTITUMOR DRUGSAnnual Review of Biochemistry, 1989
- Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks.Molecular and Cellular Biology, 1988