Urinary cyclophosphamide assay as a method for biological monitoring of occupational exposure to cyclophosphamide
- 1 June 1986
- journal article
- research article
- Published by Springer Nature in Internationales Archiv für Arbeitsmedizin
- Vol. 58 (2) , 151-155
- https://doi.org/10.1007/bf00380766
Abstract
Urine of twenty hospital workers was monitored for the excretion of the cytostatic drug cyclophosphamide using GC-MSD. The drug was found to be present above the detection limit of 0.5 μg/24 h urine in five cases. A clear relationship between cyclophosphamide handling and the detectability of excretion existed. This method developed can be of use for biological monitoring studies directed toward the finding of exposure hazards.This publication has 9 references indexed in Scilit:
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