Mechanism of enhancement of eccrine sweating by localized heating.

Publisher Website
Google Scholar
Abstract
The mechanisms by which localized heating produces an increase in human eccrine sweating were studied utilizing resistance hygrometry recording techniques. When a small skin region is heated from 36 to 40 C in a warm room during generalized eccrine sweating, a localized increase in sweating is produced. This increased sweat production can be blocked by the parasympatholytic agents like atropine and hemicholinium, by arterial occlusion, and by exposure in a cool room. Sweating activity depressed by arterial occlusion or hemicholinium could not be stimulated by local heating, but could be stimulated by pilocarpine, a parasympathomimetic drug. Physostigmine, an anticholinesterase drug, produced an augmented sweating response when local heating was applied. The hypothesis which best describes the experimental results obtained suggests that local heating acts by increasing the amount of neuroglandular transmitter substance released for each nerve impulse arriving at the preglandular nerve terminals.

This publication has 1 reference indexed in Scilit: