STUDIES ON THE MECHANISM OF NIDATION. XVII. HISTOCHEMICAL ANALYSIS OF DECIDUALIZATION IN THE RAT

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Abstract
Histochemical observations were made on the activities of adenosinetriphosphatase, alkaline and acid phosphatase, and on RNA, glycogen and lipids as well as connective tissue elements in uteri of pseudopregnant rats during the period of formation of deciduomata, i. e. between 36 to 96 hours after the administration of the inducing stimulus. Enzymic activity accompanied the formation of deciduomata, stopped at the limits of the decidual cell reaction and did not involve the rest of the endometrium. A distinct line of demarcation between the 2 tissues (deciduoma and basal endometrium) was demonstrated both histologically and histochemically. This demarcation is independent of the manner of stimulation or the extent of the decidual cell reaction.