Optimal drug and behavior therapy for treatment-refractory schizophrenic patients
- 1 May 1994
- journal article
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 151 (5) , 756-759
- https://doi.org/10.1176/ajp.151.5.756
Abstract
Thirteen treatment-refractory schizophrenic patients (10 men and three women) who were receiving more than 50 mg/day of haloperidol and who had been hospitalized for more than 1 year successfully tolerated a mean dose reduction of 63% with consequent improvement in psychopathology and side effects. The addition of intensive behavior therapy to the optimal dose of haloperidol yielded further improvements in functional behavior, such as self-care and social interaction.Keywords
This publication has 10 references indexed in Scilit:
- Prediction of response to haloperidol dose reduction by Span of Apprehension measures for treatment-refractory schizophrenic patientsAmerican Journal of Psychiatry, 1993
- Conversational skills training with schizophrenic inpatients: A study of generalization across settings and conversantsBehavior Therapy, 1993
- Haloperidol plasma levels and clinical response: a therapeutic window relationshipAmerican Journal of Psychiatry, 1992
- Optimal Dose of Neuroleptic in Acute SchizophreniaArchives of General Psychiatry, 1991
- Conversation skills training of thought-disordered schizophrenic patients through attention focusingPsychiatry Research, 1991
- A Controlled Dose Comparison of Haloperidol in Newly Admitted Schizophrenic PatientsArchives of General Psychiatry, 1990
- At Issue: Defining Treatment Refractoriness in SchizophreniaSchizophrenia Bulletin, 1990
- A Rating Scale for Drug-Induced AkathisiaThe British Journal of Psychiatry, 1989
- An Ultrasensitive Method for the Measurement of Haloperidol and Reduced Haloperidol in Plasma by High-Performance Liquid Chromatography with Coulometric DetectionTherapeutic Drug Monitoring, 1988
- Significance of Neuroleptic Dose and Plasma Level in the Pharmacological Treatment of PsychosesArchives of General Psychiatry, 1988