Cathepsin A of Two Different Molecular Sizes in Pig Kidney

Abstract
Pig kidney contained two different molecular sizes of cathepsin A. The enzymes of larger molecular size (cathepsin A, L; MW>500,000) and of smaller molecular size (cathepsin A, S; MW=100,000) were separated by gel chromatography on Sephadex or by sucrose gradient centrifugation. The two enzymes have different physical properties but very similar enzymatic properties. These enzymatic properties are almost same as those of crude enzyme preparation.

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