EFFECTS OF OZONE ON SYMPTOMS AND CARDIOPULMONARY FUNCTION IN A FLIGHT ATTENDANT SURROGATE POPULATION

  • 1 January 1980
    • journal article
    • research article
    • Vol. 51  (3) , 237-246
Abstract
Two studies were conducted to ascertain the lowest ozone concentration threshold for statistically significant adverse effects on cardiopulmonary function and symptoms in male and female surrogates of the flight attendant population. Both studies simulated in-flight environmental conditions at 1829 m mean sea level (MSL) chamber altitude. The ozone exposures were 0.2 ppm by volume (ppmv) for 4 h in the 1st study and 0.3 ppmv for 3 h in the 2nd study. Each subject was similarly exposed to air only (no ozone) on another occasion. Treadmill exercise, equivalent to workloads of on-duty flight attendants, was performed at altitude. Cardiorespiratory measurements were made during ozone exposure. Spirometry and symptom assessments were made immediately before and after exposure. The ozone threshold for reversible adverse effects on symptoms and spirometry function was reached by a 3-h exposure to 0.3 ppmv. A greater symptomatic sensitivity to ozone apparently exists in females.