An ultrasensitive nucleic acid biosensor based on the catalytic oxidation of guanine by a novel redox threading intercalator
- 11 January 2005
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Chemical Communications
- No. 8,p. 1064-1066
- https://doi.org/10.1039/b411803k
Abstract
An ultrasensitive nucleic acid biosensor for the direct detection of attomoles nucleic acid in 1.0 µl droplets is described which can be used for detection of cancer marker genes in mRNA extracted from human breast tissues without a RT-PCR step.Keywords
This publication has 20 references indexed in Scilit:
- A Nucleic Acid Biosensor for Gene Expression Analysis in Nanograms of mRNAAnalytical Chemistry, 2004
- Amperometric Detection of Nucleic Acid at Femtomolar Levels with a Nucleic Acid/Electrochemical Activator Bilayer on Gold ElectrodeAnalytical Chemistry, 2004
- Detection of Attomole Quantitites of DNA Targets on Gold Microelectrodes by Electrocatalytic Nucleobase OxidationAnalytical Chemistry, 2003
- Modification of Indium Tin Oxide Electrodes with Nucleic Acids: Detection of Attomole Quantities of Immobilized DNA by ElectrocatalysisAnalytical Chemistry, 2000
- Guinea Pig p53 mRNA: Identification of New Elements in Coding and Untranslated Regions and Their Functional and Evolutionary ImplicationsGenomics, 1999
- Polishable and Renewable DNA Hybridization BiosensorsAnalytical Chemistry, 1998
- Quartz Crystal Microbalance Study of DNA Immobilization and Hybridization for Nucleic Acid Sensor DevelopmentAnalytical Chemistry, 1997
- DNA Electrochemical Biosensor for the Detection of Short DNA Sequences Related to the Human Immunodeficiency VirusAnalytical Chemistry, 1996
- Lösliche Perylen‐Fluoreszenzfarbstoffe mit hoher PhotostabilitätEuropean Journal of Inorganic Chemistry, 1982
- Interaction of aromatic imides with DNA. 1. Spectrophotometric and viscometric studiesBiochemistry, 1982