Auranofin (Sk + F 39162) Induced Enterocolitis in Rheumatoid Arthritis: A Case Report
- 31 December 1982
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Rheumatology
- Vol. 12 (3) , 254-256
- https://doi.org/10.3109/03009748309098544
Abstract
A case of gold-induced enterocolitis in a 69-year-old female with rheumatoid arthritis who had received the new gold compound by oral administration (Auranofin (AF) for 4 weeks) is reported. Mild diarrhoea is a commonly described side effect accompanying AF, but in this case a severe colitis developed. The course of this case is very similar tothose reported regarding Myo-chrysin. The pathogenesis is discussed. It might be a direct toxic effect on the mucosa of the bowel, evidenced by the relatively high excretion of oral gold with faeces.This publication has 4 references indexed in Scilit:
- Management of rheumatoid arthritis with oral goldArthritis & Rheumatism, 1979
- Auranofin. New oral gold compound for treatment of rheumatoid arthritis.Annals of the Rheumatic Diseases, 1976
- Case reports. Severe enterocolitis complicating chrysotherapy.Annals of the Rheumatic Diseases, 1973
- Gold Reaction PanenteritisRadiology, 1972