Hearing in Guinea Pigs Deficient in the Anti-Stiffness Factor.

Abstract
68 guinea pigs deficient in the anti-stiffness factor (for at least 11 mos. before the expt. began) and 68 stock guinea pigs were subjected to audio-signals, varying from 150 to 17,000 cycles per sec, over a period of 7 mos. The ear flick response was used as the criterion of hearing. All the non-deficient animals showed normal hearing response, the most restricted range being 2000-10,000 cycles/sec. 11 deficient animals gave no hearing response during the exptl. period. By the end of the period, 8 more animals had become deaf. Thus 28% of the deficient animals were deaf according to the ear flick test and 0% of the stock animals. Statistical analysis showed that stock animals had significantly wider range of response to audio-signals than animals dificient in anti-stiffness factor.
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