DEGREE OF SULFATION IN MUCOPOLYSACCHARIDE SULFATES IN NORMAL AND STONE-FORMING URINES

  • 1 January 1976
    • journal article
    • research article
    • Vol. 14  (1) , 33-37
Abstract
Mucopolysaccharides were extracted from both normal and stone-forming patients'' urine, and those from the stone-forming samples showed a higher degree of sulfation than those from normal urines, as determined by sulfate analysis and electrophoretic measurement. The sulfated mucopolysaccharides from stone-forming urines formed insoluble Ca salts, whereas those from normal urines generally remained soluble in the presence of Ca2+. Rachitic rat cartilage also had more highly sulfated mucopolysaccharides than normal rat cartilage. Highly sulfated mucopolysaccharides appear to be a significant factor in Ca stone formations.

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