Preparation of nucleotide mimics with potent inhibitory activity against HIV reverse transcriptase
- 1 January 1991
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 12,p. 3378-3379
- https://doi.org/10.1039/p19910003378
Abstract
The triphosphate 11 has been synthesised in eight steps from 6-oxabicyclo[3.1.0]hex-2-ene 6 and has been shown to inhibit the enzyme, human immunodeficiency virus reverse transcriptase (HIV-rt).Keywords
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