Norepinephrine and gamma‐aminobutyric acid in amyotrophic lateral sclerosis
- 1 January 1980
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 30 (1) , 98
- https://doi.org/10.1212/wnl.30.1.98
Abstract
Patients with amyotrophic lateral sclerosis have increased levels of the neurotransmitter norepinephrine in blood and cerebrospinal fluid and depressed levels of the inhibitory neurotransmitter gamma-aminobutyric acid in cerebrospinal fluid. These neurochemical alterations are most marked in patients bedridden with advanced disease, appear interrelated, and lead to cardiovascular alterations in patients with amyotrophic lateral sclerosis.This publication has 3 references indexed in Scilit:
- Plasma Levels of NorepinephrineAnnals of Internal Medicine, 1978
- Suppression by GABAergic drugs of the locomotor stimulation induced by morphine, amphetamine, and apomorphine: Evidence for both pre- and post-synaptic inhibition of catecholamine systemsJournal Of Neural Transmission-Parkinsons Disease and Dementia Section, 1977
- Use of plasma norepinephrine for evaluation of sympathetic neuronal function in manLife Sciences, 1976