Tumor dose specification of I-125 seed implants

Publisher Website
Google Scholar
Abstract
A new calculation procedure for interstitial implants with 125I seeds is presented. The total activity of 125I seeds required to deliver a net minimum dose of 1 Gy [gray] is also given as a function of implant volume for various seed spacings. This will permit clinicians to prescribe a specific dose for patients as a primary or boost treatment. Elongation and shape corrections are studied. Discussions and comparisons with other dosimetric calculations such as matched peripheral dose, average minimum dose, and minimum peripheral dose are made. For a fixed total activity the net minimum dose is relatively insensitive to variations in seed spacing and individual seed activity.