MEHIXENE HYDROCHLORIDE AND PARKINSONIAN TREMOR
- 1 September 1967
- journal article
- research article
- Published by Hindawi Limited in Acta Neurologica Scandinavica
- Vol. 43 (4) , 535-538
- https://doi.org/10.1111/j.1600-0404.1967.tb05760.x
Abstract
Sixteen patients with persistent Parkinsonian tremor of various etiologies (but in no case drug-induced) volunteered for a double-blind controlled therapeutic trial of the drug methixene hydrochloride, in dosage of 45 mg/day. Tremor was measured at the wrist with a special transducer and recorded on a moving strip of paper. Fourteen patients completed the trial and statistical analysis failed to show any advantage of the drug over placebo (p> 0.1). Among the side effects noted, dry mouth and dizziness were the most significant. Possible reasons for failure of the drug to show any significant value are discussed.This publication has 1 reference indexed in Scilit:
- THERAPEUTIC ACTION OF METHIXENE HYDRO‐CHLORIDE ON PARKINSONIAN TREMOR AND A DESCRIPTION OF A NEW TREMOR‐RECORDING TRANSDUCERBritish Journal of Pharmacology and Chemotherapy, 1966