Stereocontrolled Total Synthesis of (+)-Vinblastine
- 16 February 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 124 (10) , 2137-2139
- https://doi.org/10.1021/ja0177049
Abstract
A stereocontrolled total synthesis of (+)-vinblastine was accomplished, featuring preparations of the two indole units by means of a novel indole synthesis via radical cyclization of thioanilide, and a stereoselective coupling of these units.Keywords
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