Quantitative analysis of plasminogen activator in small arteries by modified fibrin plates

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Abstract
The assay of plasminogen activator at the intimal surfaces of arteries less than 2 mm in diameter is possible using streptokinase‐ treated fibrin plates. Femoral arteries obtained from rats showed a reproducible fibrinolysis at their intimal surfaces that could be quantitated for the analysis of plasminogen activator. Utilization of the assay adjusted to the experimental situation would give a method of evaluating changes in the concentration of plasminogen activator at the intimal surface of small arteries when studied under various research conditions.