Cat Hemoglobin: p H-Dependent Cooperativity of Oxygen Binding

Abstract
Cat hemoglobin has a lower cooperativity and oxygen affinity than most mammalian hemoglobins. In contrast to the usual invariance of cooperativity with p H, a rise in cooperativity with p H is predicted by the allosteric model for low-affinity hemoglobins. Such a p H-dependent cooperativity for cat hemoglobin has been found.