Humoral and cell‐mediated responses toMalassezia pachydermatisin healthy dogs and dogs withMalasseziadermatitis
Open Access
- 3 October 1998
- journal article
- Published by Wiley in Veterinary Record
- Vol. 143 (14) , 381-384
- https://doi.org/10.1136/vr.143.14.381
Abstract
The in vitro proliferative responses of peripheral blood mononuclear cells from seven healthy basset hounds exposed toMalassezia pachydermatisantigen (500 μg/ml) exceeded (PM pachydermatisand eight Irish setters with glutensensitive enteropathy. The stimulation indices in the latter two groups and in eight healthy beagles were comparable. The stimulation indices of the four groups after exposure to phytohaemaglutinin did not differ significantly. The serum titres ofM pachydermatis‐specific IgG and IgA measured by enzymelinked immunosorbent assays (ELISA) in 21 seborrhoeic basset hounds and 11 affected dogs of various breeds exceeded those of 14 healthy basset hounds and eight healthy beagles (P<0.01 for IgG, P<0.05 for IgA). Total serum IgA concentrations measured by ELISA in the affected dogs were not lower than those of healthy dogs.Keywords
Funding Information
- Wellcome
This publication has 11 references indexed in Scilit:
- Skin and mucosal populations of Malassezia pachydermatis in healthy and seborrhoeic Basset HoundsVeterinary Dermatology, 1997
- Effects ofPityrosporum ovale on proliferation, immunoglobulin (IgA, G, M) synthesis and cytokine (IL-2, IL-10, IFNγ) production of peripheral blood mononuclear cells from patients with seborrhoeic dermatitisArchives of Dermatological Research, 1996
- Factors associated with elevated cutaneous Malassezia p a chyderm a tis populations in dogs with Pruritic skin iseaseJournal of Small Animal Practice, 1996
- Population sizes and frequency of Malassezia pachydermatis at skin and mucosal sites on healthy dogsJournal of Small Animal Practice, 1995
- Comparison of two shampoos for treatment ofMalassezia pachydermatis‐associated seborrhoeic dermatitis in basset houndsJournal of Small Animal Practice, 1995
- Use of contact plates for the quantitative culture ofMalassezia pachydermatisfrom canine skinJournal of Small Animal Practice, 1994
- Factors associated with and prevalence of high Malassezia pachydermatis numbers on dog skinJournal of the American Veterinary Medical Association, 1992
- Location of immunoglobulins and complement (C3) at the surface and within the skin of dogsJournal of Comparative Pathology, 1983
- Lymphocyte transformation suppression caused by pyoderma—Failure to demonstrate it in uncomplicated demodectic mangeComparative Immunology, Microbiology and Infectious Diseases, 1983
- Cell-Mediated Immunity to Pityrosporum Orbiculare in Tinea VersicolorJournal of Clinical Investigation, 1978