SERUM AMYLOID P-COMPONENT LEVELS IN AMYLOIDOSIS, CONNECTIVE-TISSUE DISEASES, INFECTION, AND MALIGNANCY AS COMPARED TO NORMAL SERUM
- 1 January 1979
- journal article
- research article
- Vol. 94 (4) , 633-638
Abstract
A highly sensitive radioimmunoassay was developed to measure the serum levels of SAP [serum P-component]. Sera from 50 normal individuals ranging in age from 4-89 yr had a mean level of 7.47 mg/dl and showed no variations with age. Sera from persons with various clinical types of amyloidosis, connective tissue diseases and bacterial pneumonia did not differ significantly from normal values. A significant difference was noted in the sera from persons with malignancy, where a mean value of 10.79 mg/dl was determined. Although a number of similarities exist between SAP and CRP [C-reactive protein], SAP does not share the property of being an acute-phase reactant.This publication has 13 references indexed in Scilit:
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