Alveolar Deposition of Sized Particles of 239 PuO 2 in the Mouse

Abstract
Data on the alveolar deposition of 239PuO2 particles in the mouse are presented. Alveolar deposition falls with increasing activity median aerodynamic diameter (AMAD) over the range 0.6-2.4 .mu.m. In the mouse, any peak in alveolar deposition must occur at an AMAD of less than 1 .mu.m. Information is also provided on the relative lobar concentrations (RLC) of 239PuO2. The RLC is greatest in the right apical lobe and increases quite sharply with AMAD. The RLC of the other lobes of the right lung decline with AMAD. The RLC in the left lobe is relatively unaffected by AMAD.