Experimental Dental Caries V. The Effects of Desalivation and Castration on Caries and Fluorine Storage in the Rat
- 1 March 1954
- journal article
- research article
- Published by Elsevier in Journal of Nutrition
- Vol. 52 (3) , 345-353
- https://doi.org/10.1093/jn/52.3.345
Abstract
The effects of desalivation and castration on dental caries and the storage of fluorine in the skeletal system are reported. Desalivation resulted in a marked increase in the incidence and severity of dental caries. Castration, on the other hand, in both sexes reduced caries development significantly. A sex difference in the storage of fluorine was noted, with females storing higher amounts than males. Fluorine storage under ad libitum feeding conditions indicated less fluorine in both males and females in the skeletons of the desalivated, castrated or combined desalivated-castrated groups, but under paired-feeding conditions the differences in fluorine storage between the desalivated and control groups disappeared. Fluorine storage in desalivated animals appears to be related to body growth and food ingestion in both males and females, but the fluorine storage data for a castrated and for a combined desalivated-castrated female group indicate that additional information is needed.Keywords
This publication has 3 references indexed in Scilit:
- Effect of Gonadectomy and Sex Hormones on the Structure of the Rat Salivary GlandsJournal of Dental Research, 1953
- Experimental Dental CariesJournal of Dental Research, 1952
- Effects of Stannous Fluoride, Stannous Chloride and Sodium Fluoride on the Incidence of Dental Lesions in Rats Fed a Caries-Producing DietThe Journal of the American Dental Association, 1950