Molecular Characterization of the vanE Gene Cluster in Vancomycin-Resistant Enterococcus faecalis N00-410 Isolated in Canada
Open Access
- 1 June 2002
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 46 (6) , 1977-1979
- https://doi.org/10.1128/aac.46.6.1977-1979.2002
Abstract
The vanE operon was characterized from Enterococcus faecalis N00-410 (MIC of vancomycin = 24 μg/ml). The organization of the vanE operon was identical to that of the vanC1 operon from Enterococcus gallinarum , with protein identities ranging from 46 to 63%. An open reading frame located downstream of the vanE operon showed significant homology to a number of integrase genes, all of which are located downstream of the chromosomal GMP synthase gene guaA .Keywords
This publication has 15 references indexed in Scilit:
- Identification of the first vancomycin-resistant Enterococcus faecalis harbouring vanE in Canada.2001
- Comparison of Tn5397 from Clostridium difficile, Tn916 from Enterococcus faecalis and the CW459tet(M) element from Clostridium perfringens shows that they have similar conjugation regions but different insertion and excision modules The GenBank accession numbers for the sequences in this paper are AF333235 (Tn5397) and AF329848 [part of CW459tet(M)].Microbiology, 2001
- Whole genome sequencing of meticillin-resistant Staphylococcus aureusThe Lancet, 2001
- Glycopeptide-resistant enterococci: a decade of experienceJournal of Medical Microbiology, 1998
- Gapped BLAST and PSI-BLAST: a new generation of protein database search programsNucleic Acids Research, 1997
- Glycopeptide resistance in enterococciTrends in Microbiology, 1996
- Characterization of Tn1547, a composite transposon flanked by the IS16 and IS256-like elements, that confers vancomycin resistance in Enterococcus faecalis BM4281Gene, 1996
- Identification of chromosomal mobile element conferring high-level vancomycin resistance in Enterococcus faeciumAntimicrobial Agents and Chemotherapy, 1995
- Analysis of genes encoding D-alanine-D-alanine ligase-related enzymes in Enterococcus casseliflavus and Enterococcus flavescensAntimicrobial Agents and Chemotherapy, 1994
- Sequence of the vanC gene of Enterococcus gallinarum BM4174 encoding a d-alanine:d-alanine ligase-related protein necessary for vancomycin resistanceGene, 1992