Studies on a pyrimidine phosphoribosyltransferase from murine leukemia P1534J. Partial purification, substrate specificity, and evidence for its existence as a bifunctional complex with orotidine 5-phosphate decarboxylase.
Open Access
- 1 July 1975
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 250 (13) , 5097-5108
- https://doi.org/10.1016/s0021-9258(19)41283-0
Abstract
No abstract availableKeywords
This publication has 35 references indexed in Scilit:
- Dissociation by elastase digestion of enzyme complex catalyzing the initial steps of pyrimidine biosynthesis in rat liverBiochemical and Biophysical Research Communications, 1973
- Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymesBiochemistry, 1973
- Alteration of quaternary structural behaviour of an hepatic orotate phosphoribosyltransferase-orotidine-5′-phosphate decarboxylase complex in rats following allopurinol therapyBiochemical Pharmacology, 1972
- Studies on the coordinate activity and lability of orotidylate phosphoribosyltransferase and decarboxylase in human erythrocytes, and the effects of allopurinol administrationJournal of Clinical Investigation, 1971
- Uridine‐5′‐monophosphate pyrophosphorylase activity from Escherichia coliFEBS Letters, 1969
- Synthesis of 5-fluorouridine 5′-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin—II. Correlation between the tumor levels of the enzyme and the 5-fluorouracil-promoted increase in survival of tumor-bearing miceBiochemical Pharmacology, 1969
- Synthesis of 5-fluorouridine 5'-phosphate by a pyrimidine phosphoribosyltransferase of mammalian origin. I. Some properties of the enzyme from P1534J mouse leukemic cellsBiochemistry, 1969
- DISC ELECTROPHORESIS – II METHOD AND APPLICATION TO HUMAN SERUM PROTEINS*Annals of the New York Academy of Sciences, 1964
- Metabolism of uracil and 5-fluorouracil by drug-sensitive and by drug-resistant bacteriaBiochimica et Biophysica Acta, 1960
- Formation of Uridine Phosphates from Uracil in Extracts of Ehrlich Ascites Tumor.Acta Chemica Scandinavica, 1957