Antiparasitic Drugs
- 2 May 1996
- journal article
- review article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 334 (18) , 1178-1184
- https://doi.org/10.1056/nejm199605023341808
Abstract
Infections with parasitic helminths and protozoa are important causes of morbidity and mortality worldwide. Chemotherapy has an important role not only in the treatment of individual patients but also, in conjunction with public health and vector-control measures, in reducing the transmission of parasitic infections. At present, however, there are no vaccines for human parasitic infections, the scientific knowledge necessary to develop antiparasitic drugs is rudimentary, and the mechanisms of action of most antiparasitic drugs are poorly understood. Commercial incentives for the production of drugs designed to fight infections that are mainly endemic in developing countries are limited, and some proved . . .Keywords
This publication has 87 references indexed in Scilit:
- Mode of action of benzimidazolesPublished by Elsevier ,2003
- A randomized controlled trial comparing mebendazole and albendazole against Ascaris, Trichuris and hookworm infectionsTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
- Percutaneous treatment of hydatid cysts under sonographic guidanceDigestive Diseases and Sciences, 1994
- Treatment of Strongyloides stercoralis infection with ivermectin compared with albendazole: results of an open study of 60 casesTransactions of the Royal Society of Tropical Medicine and Hygiene, 1994
- Praziquantel: The enigmatic antiparasiticParasitology Today, 1992
- Clinical Pharmacokinetics of Albendazole in Patients with Brain CysticercosisThe Journal of Clinical Pharmacology, 1992
- A field study of the effects of ivermectin on ectoparasites of manTransactions of the Royal Society of Tropical Medicine and Hygiene, 1991
- A Controlled Trial of Ivermectin and Diethylcarbamazine in Lymphatic FilariasisNew England Journal of Medicine, 1990
- Treatment and Prophylaxis ofIsospora belliInfection in Patients with the Acquired Immunodeficiency SyndromeNew England Journal of Medicine, 1989
- Clinical Manifestations and Therapy ofIsospora belliInfection in Patients with the Acquired Immunodeficiency SyndromeNew England Journal of Medicine, 1986