Abstract
Application of an epidemiologic strategy, involving repeated annual screening, public relations activities and treatment to selected groups (human), for syphilis control in 4 communities is described. The predictive value of the VDRL [Veneral Disease Research Laboratory Fast] screening test was influenced by the titer of the test and the age and location of individuals on whom it was performed. The predictive value of 1:8 VDRL titers (for active syphilis) varied from 0 in individuals 50 yr of age in community, to 0.96 in individuals 10-29 yr old in another. Reduction in transmission of infection was closely related to the degree of screening coverage of the community and adjacent communities within which intercourse occurred.

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