Site of Hydrolysis of Collagen by Hot Trichloroacetic Acid
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in Connective Tissue Research
- Vol. 4 (3) , 149-153
- https://doi.org/10.3109/03008207609152212
Abstract
When calfskin collagen is treated with trichloroaceti c acid at 90°C, it is hydrolyzed to a mixture of pep-tides, some of which are quite small. Cleavage of collagen by acid seems to occur at bonds between pro-line (or hydroxyproline) and other amino acids, with only a limited specificity for which amino acid donates its amino group to the susceptible peptide bond.This publication has 12 references indexed in Scilit:
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