BIOTRANSFORMATION OF BENZO(a)PYRENE TO DNA-BINDING PRODUCTS BY ISOLATED HEPATOCYTES

This publication has 10 references indexed in Scilit:

• Differences in the repair of DNA strand breaks induced by 9-hydroxy-benzo(a)pyrene and trans-7,8-dihydro-7,8-dihydroxy-benzo(a)pyrene in cultured human fibroblasts
  Biochemical and Biophysical Research Communications, 1978
• Formation of DAN-binding products from isolated benzo[a]pyrene metabolites in rat liver nuclei
  Chemico-Biological Interactions, 1978
• Benzo[a]pyrene diol epoxide covalently binds to deoxyguanosine and deoxyadenosine in DNA
  Nature, 1977
• Metabolism of benzo(a)pyrene with isolated hepatocytes and the formation and degradation of DNA-binding derivatives.
  Journal of Biological Chemistry, 1977
• The role of 9‐hydroxybenzo(a)pyrene in the microsome mediated binding of benzo(a)pyrene to dna
  International Journal of Cancer, 1976
• (+/-)-7alpha,8beta-dihydroxy-9beta,10beta-epoxy-7,8,9,10-tetrahydrobenzo(a)-pyrene is an intermediate in the metabolism and binding to DNA of benzo(a)pyrene.
  Proceedings of the National Academy of Sciences, 1976
• Fluorescence spectral evidence that benzo(a)pyrene‐DNA products in mouse skin arise from diol‐epoxides
  FEBS Letters, 1975
• Chemical Carcinogenesis
  Annual Review of Biochemistry, 1975
• Metabolic activation of benzo(a)pyrene proceeds by a diol-epoxide
  Nature, 1974
• Epoxides in Polycyclic Aromatic Hydrocarbon Metabolism and Carcinogenesis
  Advances in Cancer Research, 1974