Abstract
Some requirements of gene control systems in relation to differentiation in higher organisms are formulated with reference to known regulatory systems in microorganisms; the possibilities to detect these systems in Drosophila are examined. A system composed of bristle mutants, ac+ and sc+ as "structural genes," Hw+ as "operator" and h+ and/or pyd+ as "regulator," is shown to answer many of the formal requirements of such a control system.

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