Effects on Cerebral Blood Flow of Infusion of Hyperosmolar Saline During Cerebral Vasodilation in the Dog
- 1 April 1981
- journal article
- research article
- Published by Wiley in Acta Anaesthesiologica Scandinavica
- Vol. 25 (2) , 153-157
- https://doi.org/10.1111/j.1399-6576.1981.tb01626.x
Abstract
In 6 anesthetized dogs, cerebrovascular reaction to experimental hyperosmolality (plasma osomality in the range of 350-400 mosm/kg water) induced by i.v. infusion of 0.6 M saline was studied. To provoke and reinforce any effects from saline passage over the blood-brain barrier, pre-experimental submaximal vasodilation was induced by means of hypercapnia and in some cases hemodilution. Cerebral blood flow (CBF) was measured by the radioactive gas elimination method. CBF was unaffected by progressive hyperosmolality during a 2 h observation period.This publication has 15 references indexed in Scilit:
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