The effect of aromatic retinoid RO 10-9359 (etretinate) on fingernail growth

Abstract
Fingernail growth was studied in 28 patients who were receiving systemic treatment with the aromatic retinoid, Ro 10-9359 known as Tigason (etretinate; AR). A group of 15 patients with psoriasis was compared with a group of 13 patients with other dermatoses which are known to have a good response to AR therapy. In the second group, oral therapy with AR appeared to have no effect on the daily growth rate of fingernails (99±4 μm). With AR treatment, the nail-plate growth rate in the psoriatics increased to 132±5 μm.

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